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Browsing by Author "Kiboi, Nathan G."

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Adiponectin secretion in HIV-infected subjects with or without antiretroviral treatment and illicit substance use: clinical review and update

Kiboi, Nathan G.; Karanja, Joseph K.; Nebere, Saraphine N. (2016-07)

Adiponectin (Acrp30) is a novel polypeptide classified among adipokines that are chiefly secreted by adipocytes within adipose tissue. Besides the adipose tissue, levels of the adipocytokine also circulate in human ...
Antimicrobial potency of methanolic leaf extracts from selected medicinal plants against Staphylococcus aureus

Rachuonyo, H. O.; Ogola, P. E.; Arika, W. M.; Kiboi, Nathan G.; Wambani, J. R. (2016)

The main aim of the study was to test for the antimicrobial potency of Aloe secundiflora, Bulbine frutescens, Tagetes minuta and Vernonia lasiopus against Staphylococcus aureus. All the plants showed a pronounced antimicrobial ...
Comparison of microscopy and PCR for detection of Giardia lamblia and Entamoeba histolytica in human stool specimens in a resource limited setting in western Kenya

Emisiko, James; Shaviya, Nathan; Shiluli, Clement; Kiboi, Nathan G.; Wamalwa, Ronald; Jumba, Bernard; Zablon, Jeremiah; Mambo, Fidelis; Barasa, Mustafa (2020-11)

BACKGROUND፡ Accurate diagnosis of Giardia lamblia and Entamoeba histolytica is important since these intestinal parasites account for a significant proportion of morbidity and mortality globally. Microscopy is the key ...
Current milestones towards development of a fully deployable anti-malaria vaccine-future hope for malaria-free world: a review

Karanja, J. K.; Kiboi, Nathan G. (2016)

Despite novel global measures to combat malaria, the disease remains a considerable healthcare burden especially in resource limited settings. It accounts for over 2 million deaths per year, most of which are among ...
Evaluation of high density lipoprotein cholesterol as a predictor of diabetic nephropathy in type 1 diabetic patients

Wanyama, Francis M.; Kigondu, Christine S.; Mburu, D. N.; Ngugi, N. N.; Kiboi, Nathan G. (2016-05)

Background: Diabetic nephropathy is a deadly micro vascular complication of diabetes characterized by albuminuria which manifests mainly 5 years from onset of type 1 diabetes. Currently, the gold standard for its ...
Highly active antiretroviral therapy and anti-tuberculosis drug interactions with associated clinical implications: a review

Karanja, J. K.; Kiboi, Nathan G.; Nebere, S. N.; Achieng, H. O. (2016)

Tuberculosis is the most common opportunistic infection associated with HIV/AIDS, and remains a disease of global significance. Co-infection with HIV complicates proper TB diagnosis and therapeutic outcomes. Profound i ...
Immunological interactions of tuberculosis with drugs and substance use: a systematic review and update

Kiboi, Nathan G.; Nebere, Saraphine N.; Karanja, Joseph K. (2016)

Background: Illicit drug and substance use exacerbates tuberculosis (TB) pandemic and complicates management of the disease. Cytokines play a crucial role in TB infection, and recreational drugs of abuse present a ...
Immunological profiles in HIV positive patients with or without opportunistic infections and the influence of highly active antiretroviral therapy: a systematic review and update

Wambani, J. R.; Kiboi, Nathan G.; Makori, W. M.; Ogola, P. E.; Rachuonyo, H. O. (2016)

Background: Immune abnormalities are occasioned during HIV infection consequently predisposing opportunistic infections. In part, these derangements result from impaired expression of a number of immunologically important ...
In vivo antidiabetic activity of the aqueous leaf extract of Croton macrostachyus in alloxan induced diabetic mice

Arika, W. M.; Abdirahman, Y. A.; Mawia, M. A.; Wambua, K. F.; Nyamai, D. M.; Ogola, P. E.; Kiboi, Nathan G.; Nyandoro, H. O.; Agyirifo, D. S.; Ngugi, M. P.; Njagi, E. N. M. (2015)

The folklore reports from traditional medical practitioners that Croton macrostachyus has bioactivity against several diseases including diabetes mellitus have not been scientifically evaluated. The aim of this study was ...
In vivo safety of aqueous leaf extract of Lippia javanica in mice models

Arika, W. M.; Ogola, P. E.; Abdirahman, Y. A.; Mawia, A. M.; Wambua, F. K.; Nyamai, D. W.; Kiboi, Nathan G.; Wambani, J. R.; Njagi, S. M.; Rachuonyo, H. O.; Muchori, A. N.; Lagat, R. C.; Agyirifo, D. S.; Ngugi, M. P.; Njagi, E. N. M. (2016)

Rural dwellers in Kenya often resort to herbal remedy and dietary control in the treatment of several diseases including diabetes mellitus (DM), hypertension, cancer and cardiac diseases. The therapeutic applications of ...
Mineral elements content of selected Kenyan antidiabetic medicinal plants

Arika, W. M.; Ogola, P. E.; Nyamai, D. W.; Mawia, A. M.; Wambua, F. K.; Kiboi, Nathan G.; Wambani, J. R.; Njagi, S. M.; Rachuonyo, H. O.; Emmah, K. O.; Lagat, R. C.; Muruthi, C. W.; Abdirahman, Y. A.; Agyirifo, D. S.; Ouko, R. O.; Ngugi, M. P.; Njagi, E. N. M. (2016)

The use of herbal medicine as an unconventional health treatment is gaining considerable recognition and popularity worldwide. Despite skepticism and a lack of medical evidence to support its therapeutic efficacy, use ...
Non-hepatic adverse effects of antiretroviral therapy for HIV treatment and care

Wambani, J. R.; Ogola, P. E.; Makori, A. W.; Rachuonyo, H. O.; Kiboi, Nathan G. (2016-02)

High-level viral replication occurs when HIV enters the body. Due to frequent mutations, the virus becomes resistant in the body and persists in memory T cells making it incurable. Lifelong therapy is then required ...
Phenotypic and genotypic antibiotic resistant diarrheagenic Escherichia coli pathotypes isolated from children with diarrhea in Nairobi city, Kenya

Webale, Mark K.; Guyah, Bernard; Wanjala, Christine; Nyanga, Peter L.; Webale, Sella K.; Abonyo, Collins; Kitungulu, Nicholas; Kiboi, Nathan G.; Bowen, Nancy (2020-11)

BACKGROUND፡ The marked genome plasticity of diarrheagenic Escherichia coli promotes emergence of pathotypes displaying unique phenotypic and genotypic resistance. This study examined phenotypic and genotypic antibiotic ...
Plasma interferon-gamma, interleukin-10 and adiponectin levels in HIV-1 and tuberculosis coinfected injection drug users at Bomu hospital, Mombasa, Kenya

Kiboi, Nathan G. (2022-06-17)

Sub-Saharan Africa accounts for high tuberculosis cases that result from widespread HIV infections, which is exacerbated by injection substance use. Immunologically, HIV critically impairs cell-mediated host responses ...

Browsing by Author "Kiboi, Nathan G."

Browsing by Author "Kiboi, Nathan G."

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