Abstract:
The main aim of the study was to test for the antimicrobial potency of Aloe secundiflora, Bulbine frutescens,
Tagetes minuta and Vernonia lasiopus against Staphylococcus aureus. All the plants showed a pronounced
antimicrobial activity against Staphylococcus aureus with Tagetes minuta being the most active at low
concentrations (MIC 8.9 mg/ml; MBC 10.0 mg/ml) whereas Vernonia lasiopus showing less activity (MIC 12.2 mg/ml;
MBC 14.2 mg/ml). The efficacy test was carried out using the disc diffusion method. The standard antibiotics used
were ciprofloxacin (5 µg/ml) and vancomycin (3 µg/ml) showed significant antimicrobial activity by producing zones
of inhibition of 22 mm and 25 mm respectively. Dimethyl sulphoxide and distilled water were used as negative
control. The extracts from the plants were also screened for the presence of phytochemicals with the results
showing the presence of flavonoids, alkaloids, tannins and saponins in all the extracts. The study suggested that the
selected medicinal plants can be used effectively in the treatment of bacterial infection caused by Staphylococcus
aureus.
