Abstract:
In this paper, we consider a discrete mathematical model of HIV-1 in vivo
dynamics in the presences of chemotherapy and delay in infectivity of target cells. A
novel feature in this work is that both delay in infectivity of CD4+T-cells and
chemotherapy are incorporated into the discrete HIV-1 in vivo dynamics. We establish
the necessary and sufficient condition for global stability of Disease free equilibrium. We
also perform numerical simulations which supports the obtained theoretical results.