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Browsing Journal Articles by Author "Hunja, Carol W."

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An analysis of the hydrogen cyanide concentration in four cassava varieties grown in Lukenya University farm, Makueni County, Kenya

Maitha, Purity M.; Kamau, Stephen; Kimatu, Josphert N.; Hunja, Carol W. (2022-11)
A comparative study of the physiochemical and bacteriological parameters of potable water from different sources in Kitui county, Kenya

T., Wambua; Hunja, Carol W.; Kimatu, Josphert N.; Muluvi, Geoffrey M.; Kitheka, Johnson U.; Mutiso, Festus; Githenya, L.; Ndufa, James K.; Mutati, Kennedy (IISTE, 2022-11)

Developing nations are experiencing an ever-increasing demand for safe water due to climate change and the ever-increasing human population. Various strategies including construction of shallow wells, boreholes and sand ...
Effect of transportation on stress hormones of indigenous chicken in Machakos county, Kenya

Mativo, Damaris N. N.; Kanui, Titus I.; Hunja, Carol W. (2022)

The objective of this study was to establish the effect of transportation on stress hormones of indigenous chicken in Machakos County, Kenya. The study was experimental with two treatments. The first batch of 4 hens were ...
The effectiveness of Moringa Oleifera seed coagulant in reducing the turbidity and modifying the physico-chemical characteristics of water

Kitheka, Johnson U.; Njogu, Imelda N.; Muluvi, Geoffrey M.; Hunja, Carol W.; Mutiso, Festus M.; Kioko, D.; Kimatu, Josphert N. (2022-04)

Moringa oleifera plant is unique due to its coagulation effect on turbid water. However, the extent to which the seed’s powder coagulant changes the physico-chemical characteristics of treated water has not been discussed ...
Females of HbAS genotype have reduced concentration of the malaria protective deoxyhemoglobin S than males

Waitumbi, John N.; Kifude, Carolyne M.; Hunja, Carol W.; Ogutu, Bernhards R. (Public Library of Science, 2018-09)

The quantity of the intra-erythrocytic deoxyhemoglobin S (Hb S) affects the level of protection against malaria and also the sickling phenomenon. This study reports on significantly lower concentration of Hb S in females ...
Genetic Diversity and Population Structure of Plasmodium falciparum in Lake Victoria Islands, A Region of Intense Transmission

Hunja, Carol W.; Mulenge, Felix M.; Magiri, Esther; Culleton, Richard; Kaneko, Akira; Aman, Rashid A. (American Society of Tropical Medicine and Hygiene, 2016-09-06)

Understanding the genetic structure and transmission dynamics of Plasmodium falciparum parasites in malaria-endemic regions is crucial before the implementation of interventions. Located in a high-transmission region of ...
Genetic diversity of selected Moringa oleifera lam. Provenances from the coastal region of Kenya

Ondieki, Sarah K.; Hunja, Carol W.; Muluvi, Geoffrey M.; Korir, Jackson C.; Mutiso, Festus M.; Kitheka, Johnson U.; Kioko, Danson; Kimatu, Josphert N.; Ndufa, James K.; Mutati, Kennedy (2023-07)

Moringa oleifera Lam (syn. M. Pterygosperma Gaertn) is one of the most economically important crops widely cultivated globally. Traditionally, it has been used as a remedy for conditions such as diabetes, inflammation, ...
Growth and fruiting of selected provenances of Moringa oleifera Lam. in South Eastern region of Kenya

Mutiso, Festus M.; Hunja, Carol W.; Muluvi, Geoffrey M.; Kitheka, Johnson U.; Kioko, Danson; Kimatu, Josphert N.; Ndufa, James K.; Mutati, Kennedy (2022-06)

There is increasing narrowing of the genetic base of exotic species introduced in many parts of the world. This is causing a restricted genetic diversity and consequential loss of biotic and abiotic tolerance of these ...
Impact of RTS, S/AS02A and RTS, S/AS01B on multiplicity of infections and CSP t-cell epitopes of Plasmodium falciparum in adults participating in a malaria vaccine clinical trial

S. B., Anyona; Hunja, Carol W.; C. M., Kifude; M. E., Polhemus; D. G., Heppner; Leach, A.; Lievens, M.; Ballou, R.; Cohen, J.; Sutherland, C.; Waitumbi, J. N. (2007)
Impact of RTS,S/AS02A and RTS,S/AS01B on Genotypes of P. falciparum in Adults Participating in a Malaria Vaccine Clinical Trial

Waitumbi, John N.; Anyona, Samuel B.; Hunja, Carol W.; Kifude, Carolyne M.; Polhemus, Mark E.; Walsh, Douglas S.; Ockenhouse, Chris F.; Heppner, D. Gray; Leach, Amanda; Lievens, Marc; Ballou, W. Ripley; Cohen, Joe D.; Sutherland, Colin J. (Public Library of Science, 2009-11)

Objective: RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7 strain of Plasmodium falciparum linked to the hepatitis ...
Little polymorphism at the K13 propeller locus in worldwide Plasmodium falciparum populations prior to the introduction of artemisinin combination therapies

Mita, Toshihiro; Culleton, Richard; Takahashi, Nobuyuki; Nakamura, Masatoshi; Tsukahara, Takahiro; Hunja, Carol W.; Win, Zin Z.; Htike, Wah W.; Marma, Aung S.; Dysoley, Lek; Ndounga, Mathieu; Dzodzomenyo, Mawuli; Akhwale, Willis S.; Kobayashi, Jun; Uemura, Haruki; Kaneko, Akira; Hombhanje, Francis; Ferreira, Marcelo U.; Björkman, Anders; Endo, Hiroyuki; Ohashi, Jun (American Society for Microbiology, 2016)

The emergence and spread of artemisinin-resistant Plasmodium falciparum is of huge concern for the global effort toward malaria control and elimination. Artemisinin resistance, defined as a delayed time to parasite clearance ...
Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART

Hunja, Carol W.; Kitawi, Rose C.; Aman, Rashid; Ogutu, Bernhards R.; Muigai, Anne W. T.; Kokwaro, Gilbert O.; Ochieng, Washingtone (BioMed Central, 2017-02-14)

Background HIV-1 is highly variable genetically and at protein level, a property it uses to subvert antiviral immunity and treatment. The aim of this study was to assess if HIV subtype differences were associated with ...
Predisposing factors for HIV infection among injecting drug users in Malindi Sub-County, Kenya

Ng’ong’a, Gabriel O.; Hunja, Carol W.; Osman, Saida; Lwembe, Raphael M. (2016-01)

Injecting drug use (IDU) offers a100% chance to transmit blood borne infections. There exist scanty reports on factors predisposing IDUs to HIV infection and spread in Malindi Sub-county. IDUs are a potential bridging ...
The Toll-Like Receptor 2 agonist PEG-Pam2Cys as an immunochemoprophylactic and immunochemotherapeutic against the liver and transmission stages of malaria parasites

Ernest, M.; Hunja, Carol W.; Arakura, Y.; Haraga, Y.; Abkallo, H. M.; Zeng, W.; Jackson, D. C.; Chua, B.; Culleton, R. (Elsevier, 2018-12)

Both vaccine and therapeutic approaches to malaria are based on conventional paradigms; whole organism or single antigen epitope-based vaccines administered with or without an adjuvant, and chemotherapeutics (anti-malaria ...
Travellers as sentinels: Assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in Plasmodium falciparum using malaria cases imported into Scotland

Hunja, Carol W.; Unger, Holger; Ferreira, Pedro E.; Lumsden, Richard; Morris, Sheila; Aman, Rashid; Alexander, Claire; Mita, Toshihiro; Culleton, Richard (Elsevier, 2013-10)

There is growing evidence that Plasmodium falciparum parasites in southeastern Asia have developed resistance to artemisinin combination therapy. The resistance phenotype has recently been shown to be associated with four ...

Browsing Journal Articles by Author "Hunja, Carol W."

Browsing Journal Articles by Author "Hunja, Carol W."

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