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Browsing by Subject "Antinociception"

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Activation of mu, delta or kappa opioid receptors by DAMGO, DPDPE, U-50488 or U-69593 respectively causes antinociception in the formalin test in the naked mole-rat (Heterocephalus glaber)

Kanui, Titus I.; Towett, Philemon K.; Juma, Francis; Ole Miaron, Jacob Olongida; Ole Maloiy, Geoffrey M. (Elsevier, 2009-02)

Data available on the role of the opioid systems of the naked mole-rat in nociception is scanty and unique compared to that of other rodents. In the current study, the effect of DAMGO, DPDPE and U-50488 and U-69593 on ...
The antinociceptive activity of ethanolic extracts of ocimum kilimandscharicum baker ex gürke and ocimum Kenyense ayob. Ex A.J. Paton leaves

Kanui, Titus I.; Mwangi, P. W.; Wambugu, S. N.; Kariuki, D. K.; Mbugua, P. M. (2012)

Ocimum kilimandscharicum and Ocimum kenyense are two closely related species endemic to Kenya. They find wide application in a diverse array of medicinal applications, including pain relief. The present investigation was ...
Antinocieptive activity of Toddalia asiatica (L) Lam. in models of central and peripheral pain

Kanui, Titus I.; Kariuki, Hellen N.; Yenesew, Abiy; Patel, Nilesh B.; Mbugua, Paul M. (Inforesights, 2012)

Toddalia asiatica within the context of traditional African medicine is a commonly used medicinal plant in East Africa for the management of pain and inflammatory conditions. It is used by the Masai in both Kenya and ...
Intrathecal administration of clonidine or yohimbine decreases the nociceptive behavior caused by formalin injection in the marsh terrapin (Pelomedusa subrufa)

Kanui, Titus I.; Makau, Christopher M.; Towett, Philemon K.; Abelson, Klas S. P. (Wiley, 2014-11)

Background: The role of noradrenergic system in the control of nociception is documented in some vertebrate animals. However, there are no data showing the role of this system on nociception in the marsh terrapins. ...
Stimulation of mu and delta opioid receptors induces hyperalgesia while stimulation of kappa receptors induces antinociception in the hot plate test in the naked mole-rat (Heterocephalus glaber)

Kanui, Titus I.; Towett, Philemon K.; Juma, Francis D. (Elsevier, 2006-12)

The antinociceptive effects of highly selective mu (DAMGO), delta (DPDPE) and kappa (U-50488 and U-69593) opioid agonists were evaluated following intraperitoneal (i.p.) administration in the naked mole-rat. A hot plate ...

Browsing by Subject "Antinociception"

Browsing by Subject "Antinociception"

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