Browsing by Author "Khamadi, Samoel A."

Browsing by Author "Khamadi, Samoel A."

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  • The Changing Trend of HIV Type 1 Subtypes in Nairobi 
    Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Lwembe, Raphael M.; Ochieng, Washingtone; Kinyua, Joyceline G.; Muriuki, Joseph K.; Lagat, Nancy; Osman, Saida; Mwangi, Joseph M.; Okoth, Fredrick A.; Elijah M. Songok (Mary Ann Liebert, 2009)
    Monitoring the distribution of HIV-1 subtypes and recombinants among infected individuals has become a priority in HIV therapy. A laboratory analysis of samples collected from HIV-positive patients attending an STI clinic ...
  • HIV Type 1 gag genetic diversity among antenatal clinic attendees in North Rift Valley, Kenya 
    Ng'ang'a, Zipporah W.; Nyagaka, Benuel; Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Makokha, Ernest P.; Kinyua, Joyceline G.; Mwangi, Joseph; Osman, Saida; Lagat, Nancy J.; Muriuki, Joseph; Okoth, Vincent; Gicheru, Michael; Songok, Elijah M. (Mary Ann Liebert, Inc., 2012)
    HIV genetic recombination and high mutation rate increase diversity allowing it to escape from host immune response or antiretroviral drugs. This diversity has enabled specific viral subtypes to be predominant in specific ...
  • HIV type 1 genetic diversity and naturally occurring polymorphisms in HIV type 1 Kenyan isolates: implications for integrase inhibitors 
    Ng'ang'a, Zipporah W.; Nyamache, Anthony K.; Muigai, Anne W. T.; Khamadi, Samoel A. (Mary Ann Liebert, Inc., 2012)
    Little is known about the extent and predictors of polymorphisms potentially influencing susceptibility to HIV integrase inhibitors. HIV-1 genetic diversity and drug resistance are major challenges in patient management globally. ...
  • HIV Type 1 Subtype Diversity and Drug Resistance among HIV Type 1-Infected Kenyan Patients Initiating Antiretroviral Therapy 
    Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Lubano, Kizito; Lwembe, Raphael; Lagat, Nancy; Kinyua, Joyceline G.; Okoth, Fredrick A.; Songok, Elijah M.; Makokha, Ernest P.; Ichimura, Hiroshi (Mary Ann Liebert, 2009-12-10)
    The treatment of HIV-1 infection with antiretroviral drugs has greatly improved the survival of those who are infected. However, HIV-1 diversity and drug resistance are major challenges in patient management, especially ...
  • HIV Type 1 Subtypes among STI Patients in Nairobi: A Genotypic Study Based on Partial pol Gene Sequencing 
    Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Kinyua, Joyceline G.; Lagat, Nancy; Magoma, Gabriel N.; Mwau, Matilu M.; Makokha, Ernest P.; Onyango, Vincent; Osman, Saida; Okoth, Fredrick A.; Songok., Elijah M. (Mary Ann Liebert, 2006-12)
    Circulating strains of human immunodeficiency virus (HIV) exhibit an extraordinary degree of genetic diversity and have been classified on the basis of relationships into distinct lineages called groups, types, subtypes, ...
  • HIV Type 1 Subtypes in Circulation in Northern Kenya 
    Kiptoo, Michael K.; Khamadi, Samoel A.; Ochieng, Washington; Lihana, Raphael W.; Kinyua, Joyceline; Muriuki, Joseph; Mwangi, Joseph; Lwembe, Raphael; Osman, Saida; Lagat, Nancy; Pelle, Roger; Muigai, Anne; Carter, Jane Y.; Oishi, Isao; Ichimura, Hiroshi; Mwaniki, D. L.; Okoth, Fredrick A.; Mpoke, Solomon; Songok, Elijah M. (Mary Ann Liebert, 2005-10-11)
    The genetic subtypes of HIV-1 circulating in northern Kenya have not been characterized. Here we report the partial sequencing and analysis of samples collected in the years 2003 and 2004 from 72 HIV-1-positive patients ...
  • Profile of HIV Type 1 coreceptor tropism among Kenyan patients from 2009 to 2010 
    Ng'ang'a, Zipporah W.; Nyamache, Anthony K.; Muigai, Anne W.T.; Khamadi, Samoel A. (Mary Ann Liebert, Inc., 2013)
    A switch of HIV coreceptor usage from CCR5 to CXCR4 occurs in AIDS pathogenesis and may play a critical role in the use of entry inhibitors. To determine the potential usefulness of maraviroc and other CCR5 antagonists ...

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