Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae

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dc.contributor.author Wanjala, Cornelius C.
dc.contributor.author Maniafu, Barasa M.
dc.contributor.author Wilber, Lwande
dc.contributor.author Ndiege, Isaiah O.
dc.contributor.author Akenga, Teresa A.
dc.date.accessioned 2014-12-16T11:38:48Z
dc.date.available 2014-12-16T11:38:48Z
dc.date.issued 2009-09
dc.identifier.citation Memórias do Instituto Oswaldo Cruz. 2009 Sep;104(6):813-7. en_US
dc.identifier.issn 0074-0276
dc.identifier.uri http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002&lng=en&nrm=iso&tlng=en
dc.identifier.uri http://hdl.handle.net/123456789/486
dc.description http://dx.doi.org/10.1590/S0074-02762009000600002 en_US
dc.description.abstract Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature. en_US
dc.language.iso en en_US
dc.publisher Instituto Oswaldo Cruz, Ministério da Saúde en_US
dc.subject Plumbago zeylanica en_US
dc.subject Plumbago stenophylla en_US
dc.subject Plumbago dawei en_US
dc.subject larvicidal activity en_US
dc.subject 5-hydroxy en_US
dc.subject 2-methyl-1,4-naphthoquinone en_US
dc.subject Anopheles gambiae en_US
dc.title Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae en_US
dc.type Article en_US


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