Abstract:
Malaria starts with the infection of the liver by
plasmodium
sporozoites. This form ofthe parasite
migrates through several host cells breaching
their plasma membranes before infecting a final
hepatocyte which they enter forming a
parasitophorous vacuole. It is still controversial
why Plasmodium sporozoites migrate through
host cells. By reviewing the most recent
literature, we hope to give an insight on the
different steps of host invasion in which
migration through cells is involved and on the
possible role forthis mechanism in infection.
