dc.contributor.author |
Ng'ang'a, Zipporah W. |
|
dc.contributor.author |
Mwangi, Joseph |
|
dc.contributor.author |
Songok, Elijah |
|
dc.contributor.author |
Kinyua, Joyceline |
|
dc.contributor.author |
Lagat, Nancy |
|
dc.contributor.author |
Muriuki, Joseph |
|
dc.contributor.author |
Lihana, Raphael |
|
dc.contributor.author |
Khamadi, Samoel |
|
dc.contributor.author |
Osman, Saida |
|
dc.contributor.author |
Lwembe, Raphael |
|
dc.contributor.author |
Kiptoo, Michael K. |
|
dc.contributor.author |
Mwau, Matilu |
|
dc.contributor.author |
Chirchir, Ruth |
|
dc.contributor.author |
Mpoke, Solomon |
|
dc.contributor.author |
Nyamongo, Jack |
|
dc.contributor.author |
Okoth, Fred |
|
dc.contributor.author |
Yamada, Rika |
|
dc.contributor.author |
Kageyama, Seiji |
|
dc.contributor.author |
Ichimura, Hiroshi |
|
dc.date.accessioned |
2014-12-03T10:51:01Z |
|
dc.date.available |
2014-12-03T10:51:01Z |
|
dc.date.issued |
2008 |
|
dc.identifier.citation |
Intervirology. 2008;51(6):417-21. |
en_US |
dc.identifier.uri |
http://www.researchgate.net/publication/24174998_Molecular_genetic_diversity_of_hepatitis_B_virus_in_Kenya |
|
dc.identifier.uri |
http://hdl.handle.net/123456789/309 |
|
dc.description |
doi: 10.1159/000205526. |
en_US |
dc.description.abstract |
Eight genotypes of hepatitis B virus (A-H) and subgenotypes have been recognized worldwide. However, there is limited information on prevalent genotypes in many countries in Africa. This study was undertaken to determine the hepatitis B virus (HBV) genotypes in Kenya. Seropositive HBV blood samples from a blood donor setting were used in the study. HBV genotypes were determined in 52 nucleic acid-positive samples using specific primer in a nested PCR and sequencing employed in the HBV genotyping. This study shows presence of HBV variants with genotypes A (88%), E (8%) and D (4%). In conclusion, we found that HBV genotype A is the most predominant genotype in Kenya with both subgenotype A1 and A2 present. Genotype D and E are also present in our population. This demonstrates that there could be a high genetic diversity of HBV in Kenya.
Copyright 2009 S. Karger AG, Basel. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
S. Karger AG, Basel |
en_US |
dc.subject |
Genotypes |
en_US |
dc.subject |
Hepatitis B virus |
en_US |
dc.subject |
Kenya |
en_US |
dc.subject |
Nuclear acid testing |
en_US |
dc.title |
Molecular genetic diversity of hepatitis B virus in Kenya |
en_US |
dc.type |
Article |
en_US |