Browsing School of Science and Computing (JA) by Author "Wanjala, Cornelius C."

Browsing School of Science and Computing (JA) by Author "Wanjala, Cornelius C."

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  • Antifeedant Activities of the Erythrinaline Alkaloids from Erythrina latissima against Spodoptera littoralis (Lepidoptera noctuidae) 
    Wanjala, Cornelius C.; Akeng’a, Teresa; Obiero, George O.; Lutta, Kweyu P. (2009)
    The antifeedant activities of the Erythrina alkaloids from the seeds, seed pods and flowers of Erythrina latissima were investigated in laboratory dual- choice bioassays using third-instar Spodoptera littoralis (Boisduval) ...
  • Antimicrobial Flavonoids from Bolusanthus speciosus 
    Wanjala, Cornelius C.; Bojase, Gomotsang; Majinda, Runner R. T.; Gashe, Berhanu A. (2002)
    A new isoflavanone namely 3,5,7,2′,4′-pentahydroxy-8,3′-di(γ,γ-dimethylallyl)isoflavanone (bolusanthin II) and four new pterocarpans identified as 3-hydroxy-6′,6′-dimethylpyrano[2′,3′:1,2] [6aR,11aR]-8,9-methylenedioxypterocarpan ...
  • Antimicrobial marine natural products from the sponge, Axinella infundibuliformis 
    Wanjala, Cornelius C.; Kweyu, P. Lutta; Bii, Christine; Akenga, Teresa A. (2008)
    The antimicrobial activity of the extracts and pure compounds from the sponge Axinella infundibuliformis collected Mombasa, the Kenyan Coast have been reported. The pure compounds were purified and characterized through ...
  • Bioactive non-alkaloidal constituents from the genus Erythrina 
    Wanjala, Cornelius C.; Majinda, Runner R. T.; Juma, Benard F. (Elsevier, 2005)
    The genus Erythrina is very rich in secondary metabolites particularly of the flavonoids class. A literature survey of non-alkaloidal secondary metabolites from Erythrina showed the presence of flavanones, flavonols, ...
  • Discovering Poisonous Plants by Tasting: The Case of Children in Mumias Sub-County, Kenya 
    Wanjala, Cornelius C.; Wanzala, Wycliffe (2016-09)
    Plants are like a two-edged sword, which cuts on either pointing side. All living organisms exclusively depend on plants for their survival while, on the other hand, the same plants, just like the two-edged sword, are ...
  • Erythrinaline alkaloids and antimicrobial flavonoids from Erythrina latissima. 
    Wanjala, Cornelius C.; Juma, Benard F.; Bojase, Gomotsang; Gashe, Berhanu A.; Majinda, Runner R. T. (2002)
    The seed pods of Erythrina latissima yielded erysotrine, erysodine, syringaresinol, vanillic acid, a new erythrina alkaloid, (+)-10,11-dioxoerysotrine, which was lethal to brine shrimp and 2-(5′-hydroxy-3′-methoxy ...
  • Flavonoid glycosides from Crotalaria podocarpa 
    Wanjala, Cornelius C.; Majinda, Runner R. T. (Elsevier, 1999-07)
    The structures of two flavonoid glycosides isolated from the aerial parts of Crotalaria podocarpa have been established as apigenin 7-O-β-d-apiofuranosyl (1→6)-β-glucopyranoside and a new compound, acacetin 7-O-β-d-apiofuranosyl ...
  • Flavonoids from the stem bark of Bolusanthus speciosus. 
    Wanjala, Cornelius C.; Bojase, Gomotsang; Majinda, Runner R. T. (Elsevier, 2001-04)
    Three flavonoids (bolusanthols A–C), viz an isoflavan and two prenylated isoflavanones, were isolated from the stem bark of Bolusanthus speciosus in addition to four known flavonoids, 5,7,3′-trihydroxy-4′-methoxy-5′-γ,γ- ...
  • In vitro antiplasmodial activity and toxicity assessment of plant extracts used in traditional malaria therapy in the Lake Victoria Region 
    Wanjala, Cornelius C.; Ayuko, Teresa A.; Njau, Richard N.; Nyangasi, Leah; Ndiege, Isiah O. (2009-08)
    As part of our program screening the flora of the Lake Victoria Region, a total of 54 organic extracts from seven plant families (8 species) were individually tested for antiplasmodial activity against chloroquine-sensitive ...
  • In vitro antiplasmodial and cyclin- dependent protein kinase (pfmrk) inhibitory activities of selected flavonoids in combination with chloroquine (CQ) and artemisinin 
    Wanjala, Cornelius C.; Akala, H. M.; Waters, C. N.; Yenesew, A.; Akenga, T. Ayuko (Academic Journals, 2010-08)
    In this study, we report in vitro chloroquine (CQ) and artemisinin combination studies of eight flavonoids against Plasmodium falciparum strains. The flavonoids were previously isolated from Erythrina sp. (Family Leguminosae) ...
  • Isoflavone glycosides from the root wood of Erythrina latissima. 
    Wanjala, Cornelius C.; Majinda, Runner R. T. (2001-03)
    The molecular structures of 3 isoflavone glycosides isolated from the root wood of Erythrina latissimawere established as 4′-hydroxyisoflavone-7-O-β-D-glucopyranoside (compound 1); 4′-hydroxyisoflavone-7-O-α-L-rhamnosyl ...
  • Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae 
    Wanjala, Cornelius C.; Maniafu, Barasa M.; Wilber, Lwande; Ndiege, Isaiah O.; Akenga, Teresa A. (Instituto Oswaldo Cruz, Ministério da Saúde, 2009-09)
    Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) ...
  • A new isoflavanone from the stem bark of Erythrina latissima 
    Wanjala, Cornelius C.; Majinda, Runner R. T. (Elsevier, 2000-08-01)
    Two isoflavonoids — including the new compound 5,7-dihydroxy-2′,4′,5′-trimethoxyisoflavanone (1) — six flavanones and a feruloyl ester were isolated from the stem bark of Erythrina latissima.
  • A new stilbene glycoside from Elephantorrhiza goetzei. 
    Wanjala, Cornelius C.; Majinda, Runner R. T. (Elsevier, 2001-08)
    A new stilbene glycoside, 5-methoxy-(E)-resveratrol 3-O-rutinoside (1) was isolated from the root bark of Elephantorrhiza goetzei, along with known compounds, namely gallic acid, (E)-resveratrol, (±)-catechin, (±)-gallocatechin ...
  • Recent results from natural product research at the University of Botswana 
    Wanjala, Cornelius C.; Majinda, Runner R. T.; Abegaz, Berhanu M.; Bezabih, Merhatibeb; Ngadjui, Bonaventure T.; Mdee, Ladislaus K.; Bojase, Gomotsang; Silayo, Alfonse; Masesane, Ishmael; Yeboah, Samuel O. (International Union of Pure and Applied Chemistry, 2001)
    Marketed plants are very important items of trade in many parts of the world. The community uses these for a variety of purposes such as foods, cosmetics, flavors, spices, and medicines. It seems that plants that are used ...
  • Two new isoflavanoids from Bolusanthus Speciosus 
    Wanjala, Cornelius C.; Bojase, Gomotsang; Majinda, Runner R. T. (2001)
    The structures of two new isoflavonoids from the combined ethyl acetate/methanolic extracts of the stem bark of Bolusanthus speciosus have been established as 4,7,2' -trihydroxy-4' -methoxyisoflavanol (1) and 5,7,3' ,4' ...
  • Two Novel Glucodienoid Alkaloids from Erythrina latissima Seeds 
    Wanjala, Cornelius C.; Majinda, Runner R. (American Chemical Society, 2000)
    The structures of two novel glycodienoid alkaloids isolated from Erythrina latissima seeds have been established as (+)-16beta-D-glucoerysopine (1) and (+)-15beta-D-glucoerysopine (2). NOE measurements established that 1 ...
  • The unique pharmaceutical potential applications of soils to livelihoods 
    Wanjala, Cornelius C.; Wanzala, Wycliffe; Murimi, Mwangi D. (2016)
    Soil is a natural resource and a mixture of many varied abiotic and biotic components, which give its true identity and value as the main component of the earth's ecosystem and a precious “skin of the earth” with interfaces ...

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