Browsing School of Science and Computing (JA) by Author "Nyamache, Anthony K."

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HIV type 1 genetic diversity and naturally occurring polymorphisms in HIV type 1 Kenyan isolates: implications for integrase inhibitors

Ng'ang'a, Zipporah W.; Nyamache, Anthony K.; Muigai, Anne W. T.; Khamadi, Samoel A. (Mary Ann Liebert, Inc., 2012)

Little is known about the extent and predictors of polymorphisms potentially inﬂuencing susceptibility to HIV integrase inhibitors. HIV-1 genetic diversity and drug resistance are major challenges in patient management globally. ...
Profile of HIV Type 1 coreceptor tropism among Kenyan patients from 2009 to 2010

Ng'ang'a, Zipporah W.; Nyamache, Anthony K.; Muigai, Anne W.T.; Khamadi, Samoel A. (Mary Ann Liebert, Inc., 2013)

A switch of HIV coreceptor usage from CCR5 to CXCR4 occurs in AIDS pathogenesis and may play a critical role in the use of entry inhibitors. To determine the potential usefulness of maraviroc and other CCR5 antagonists ...

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