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dc.contributor.authorNg'ang'a, Zipporah W.
dc.contributor.authorMwangi, Joseph
dc.contributor.authorSongok, Elijah
dc.contributor.authorKinyua, Joyceline
dc.contributor.authorLagat, Nancy
dc.contributor.authorMuriuki, Joseph
dc.contributor.authorLihana, Raphael
dc.contributor.authorKhamadi, Samoel
dc.contributor.authorOsman, Saida
dc.contributor.authorLwembe, Raphael
dc.contributor.authorKiptoo, Michael K.
dc.contributor.authorMwau, Matilu
dc.contributor.authorChirchir, Ruth
dc.contributor.authorMpoke, Solomon
dc.contributor.authorNyamongo, Jack
dc.contributor.authorOkoth, Fred
dc.contributor.authorYamada, Rika
dc.contributor.authorKageyama, Seiji
dc.contributor.authorIchimura, Hiroshi
dc.date.accessioned2014-12-03T10:51:01Z
dc.date.available2014-12-03T10:51:01Z
dc.date.issued2008
dc.identifier.citationIntervirology. 2008;51(6):417-21.en_US
dc.identifier.urihttp://www.researchgate.net/publication/24174998_Molecular_genetic_diversity_of_hepatitis_B_virus_in_Kenya
dc.identifier.urihttp://hdl.handle.net/123456789/309
dc.descriptiondoi: 10.1159/000205526.en_US
dc.description.abstractEight genotypes of hepatitis B virus (A-H) and subgenotypes have been recognized worldwide. However, there is limited information on prevalent genotypes in many countries in Africa. This study was undertaken to determine the hepatitis B virus (HBV) genotypes in Kenya. Seropositive HBV blood samples from a blood donor setting were used in the study. HBV genotypes were determined in 52 nucleic acid-positive samples using specific primer in a nested PCR and sequencing employed in the HBV genotyping. This study shows presence of HBV variants with genotypes A (88%), E (8%) and D (4%). In conclusion, we found that HBV genotype A is the most predominant genotype in Kenya with both subgenotype A1 and A2 present. Genotype D and E are also present in our population. This demonstrates that there could be a high genetic diversity of HBV in Kenya. Copyright 2009 S. Karger AG, Basel.en_US
dc.language.isoenen_US
dc.publisherS. Karger AG, Baselen_US
dc.subjectGenotypesen_US
dc.subjectHepatitis B virusen_US
dc.subjectKenyaen_US
dc.subjectNuclear acid testingen_US
dc.titleMolecular genetic diversity of hepatitis B virus in Kenyaen_US
dc.typeArticleen_US
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