Browsing by Author "Lagat, Nancy"

Browsing by Author "Lagat, Nancy"

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  • The Changing Trend of HIV Type 1 Subtypes in Nairobi 
    Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Lwembe, Raphael M.; Ochieng, Washingtone; Kinyua, Joyceline G.; Muriuki, Joseph K.; Lagat, Nancy; Osman, Saida; Mwangi, Joseph M.; Okoth, Fredrick A.; Elijah M. Songok (Mary Ann Liebert, 2009)
    Monitoring the distribution of HIV-1 subtypes and recombinants among infected individuals has become a priority in HIV therapy. A laboratory analysis of samples collected from HIV-positive patients attending an STI clinic ...
  • HIV Type 1 Subtype Diversity and Drug Resistance among HIV Type 1-Infected Kenyan Patients Initiating Antiretroviral Therapy 
    Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Lubano, Kizito; Lwembe, Raphael; Lagat, Nancy; Kinyua, Joyceline G.; Okoth, Fredrick A.; Songok, Elijah M.; Makokha, Ernest P.; Ichimura, Hiroshi (Mary Ann Liebert, 2009-12-10)
    The treatment of HIV-1 infection with antiretroviral drugs has greatly improved the survival of those who are infected. However, HIV-1 diversity and drug resistance are major challenges in patient management, especially ...
  • HIV Type 1 Subtypes among STI Patients in Nairobi: A Genotypic Study Based on Partial pol Gene Sequencing 
    Kiptoo, Michael K.; Lihana, Raphael W.; Khamadi, Samoel A.; Kinyua, Joyceline G.; Lagat, Nancy; Magoma, Gabriel N.; Mwau, Matilu M.; Makokha, Ernest P.; Onyango, Vincent; Osman, Saida; Okoth, Fredrick A.; Songok., Elijah M. (Mary Ann Liebert, 2006-12)
    Circulating strains of human immunodeficiency virus (HIV) exhibit an extraordinary degree of genetic diversity and have been classified on the basis of relationships into distinct lineages called groups, types, subtypes, ...
  • HIV Type 1 Subtypes in Circulation in Northern Kenya 
    Kiptoo, Michael K.; Khamadi, Samoel A.; Ochieng, Washington; Lihana, Raphael W.; Kinyua, Joyceline; Muriuki, Joseph; Mwangi, Joseph; Lwembe, Raphael; Osman, Saida; Lagat, Nancy; Pelle, Roger; Muigai, Anne; Carter, Jane Y.; Oishi, Isao; Ichimura, Hiroshi; Mwaniki, D. L.; Okoth, Fredrick A.; Mpoke, Solomon; Songok, Elijah M. (Mary Ann Liebert, 2005-10-11)
    The genetic subtypes of HIV-1 circulating in northern Kenya have not been characterized. Here we report the partial sequencing and analysis of samples collected in the years 2003 and 2004 from 72 HIV-1-positive patients ...
  • HIV-1 drug resistance-associated mutations among HIV-1 infected drug-naïve antenatal clinic attendees in rural Kenya 
    Ng'ang'a, Zipporah W.; Kiptoo, Michael K.; Brooks, James; Lihana, Raphael W.; Sandstrom, Paul; Kinyua, Joyceline; Lagat, Nancy; Okoth, Fredrick; Songok, Elijah M. (BioMed Central, 2013-11-03)
    Background Access to antiretroviral therapy (ART) has increased dramatically in Sub-Saharan Africa. In Kenya, 560,000 people had access to ART by the end of 2011. This scaling up of ART has raised challenges to the ...
  • Molecular genetic diversity of hepatitis B virus in Kenya 
    Ng'ang'a, Zipporah W.; Mwangi, Joseph; Songok, Elijah; Kinyua, Joyceline; Lagat, Nancy; Muriuki, Joseph; Lihana, Raphael; Khamadi, Samoel; Osman, Saida; Lwembe, Raphael; Kiptoo, Michael K.; Mwau, Matilu; Chirchir, Ruth; Mpoke, Solomon; Nyamongo, Jack; Okoth, Fred; Yamada, Rika; Kageyama, Seiji; Ichimura, Hiroshi (S. Karger AG, Basel, 2008)
    Eight genotypes of hepatitis B virus (A-H) and subgenotypes have been recognized worldwide. However, there is limited information on prevalent genotypes in many countries in Africa. This study was undertaken to determine ...
  • Prevalence of nevirapine-associated resistance mutations after single dose prophylactic treatment among antenatal clinic attendees in North Rift Kenya 
    Ng'ang'a, Zipporah W.; Kiptoo, Michael K.; Ichimura, Hiroshi; Wembe, Raphael L.; Mueke, Jones; Kinyua, Joyceline; Lagat, Nancy; Okoth, Fredrick; Songok, E. M. (Mary Ann Liebert, Inc., 2008)
    The use of single dose nevirapine to prevent mother-to-child transmission of HIV has been reported to induce drug-resistant mutations and reduce options for antiretroviral treatment for HIV-infected mothers and their children. ...
  • Switch from 200 to 350 CD4 baseline count: what it means to HIV care and treatment programs in Kenya 
    Ng'ang'a, Zipporah W.; Mwangi, Joseph; Lihana, Raphael; Lagat, Nancy; Kinyua, Joyceline; Muriuki, Joseph; Maiyo, Alex; Kinyua, Florence; Okoth, Fredrick; Mpoke, Solomon (2012)
    Introduction: With the increasing population of infected individuals in Africa and constrained resources for care and treatment, antiretroviral management continues to be an important public health challenge. Since the ...

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